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Rapid T1 mapping using Multislice EPI. Quantitative maps of T1 covering the whole brain in 2 x 2 x 2 mm3 resolution are acquired in three minutes. The images acquired at each inversion time are fitted to an inversion recovery curve using a two stage fitting algorithm which gives accurate and reliable results. T1 maps are being obtained on patients with multiple sclerosis and motor-neuron disease to test if such quantitative measurements can be used as a surrogate marker for disease progression. (see Clare, S., Jezzard, P. (2001) 'Rapid T1 Mapping using Multislice Echo Planar Imaging'. Magnetic Resonance in Medicine. 45 630-634.)