Chapter 9
Effective Paradigm Design
Authors: David Donaldson and
Randy L. Buckner
(Washington University)
Section 9.1. Introduction
Section 9.2. Origins of the Signal
9.2.1: The BOLD-contrast haemodynamic response
9.2.2: Reliability of the signal
Section 9.3. Blocked Paradigms
Section 9.4. Event-Related Paradigms
9.4.1: Rapid data acquisition
9.4.2: Sensitivity of the signal
9.4.3: Linearity of the signal
Section 9.5. Paradigm Design and Analysis of Event-Related Studies
9.5.1: Extracting the signal of interest
9.5.2: Time locked averaging
9.5.3: Trial ordering and jitter
9.5.4: Detecting the response and constructing activation maps
9.5.5: Some consequences of being event-related
9.5.6: Issues related to experimental design
Section 9.6. Introducing Mixed 'Event-Related and Blocked' Designs
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