Functional Mapping Methods

Table of Contents

PPT Slide

Functional Mapping Methods

Functional Mapping Methods

The Neuron

Brain Metabolism

CBF and CMRO2 Coupling

CBF and CMRO2 Coupling

Coupled or Uncoupled O2 Metabolism?

Oxygen Transport

Physiological Correlates of Brain Electrical Activity

Physiology: Summary

BOLD fMRI: Preview

Magnetic Properties of Hemoglobin

Magnetic Field Distortions Around a Cylinder

Magnetic Field Distortions Around a Cylinder

Variation with O2 Saturation

Gradient Echo versus Spin Echo Sensitivity to Vessel Size

fMRI BOLD: Overview

Limits to Resolution

BOLD Signal Response

Factors Affecting Spatial Resolution

How Can we Overcome Limits to Spatial Resolution?

Factors Affecting Temporal Resolution

How Can we Overcome Limits to Temporal Resolution?

So What Resolution Can be Achieved?

MRI Practicalities

MRI System Block Diagram

fMRI Additions

1D Imaging Example

1D Imaging Example

1D Imaging Example

Principle of k-Space

2D Back Projection Imaging

2D Projection Reconstruction

2D Fourier Imaging

Echo Planar Imaging

Gradient Echo EPI

Functional MRI

Data Implications

Visual Stimulation

Visual Stimulation

Image Processing

Head Motion Correction

Head Motion Correction

Head Motion Registration

Spatial Smoothing

Matched Temporal Filtering

Statistical Testing

Statistical Thresholding

Volume Rendering

Inter Subject Comparison

Inter Subject Comparison

Flatmap Representation of V1/V2

Image Analysis Research

Conclusions

Conclusions

PPT Slide

Email: peterj@fmrib.ox.ac.uk

Home Page: http://www.fmrib.ox.ac.uk

Other information:
FMRIB Centre, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, ENGLAND