Perfusion and BOLD Time Courses

Buxton et al., Proc. ISMRM, 1:153, 1997

Buxton et al., Proc. ISMRM, 1:7, 1998

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time, (sec)

signal, (%)

BOLD

Perfusion

Perfusion change more

linear to increases in

metabolic demand

BOLD signal change

asymptotes with increases

in metabolic demand.

BOLD signal confounded

by CBV changes

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